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Pharmacoset-Specific

These are the PharmacoSet Specific DNL requirements

PharmacoSet

Data Components   MolecularProfiles   treatmentResponse   sampleMetadata   treatmentMetadata                  annotationrnaseqdatatypefpkmclassSummarizedExperimentfilenamernaseq_fpkm_20220624.csvdata_source   date2024-02-26numSamples949descriptionRead counts, TPM & FPKM-values for all sequenced models including cell lines and organoids.toolTODO::(add tool)urlhttps://cog.sanger.ac.uk/cmp/download/rnaseq_all_20220624.zipannotationrnaseqdatatypetpmclassSummarizedExperimentfilenamernaseq_tpm_20220624.csvdata_source   date2024-02-26numSamples949descriptionRead counts, TPM & FPKM-values for all sequenced models including cell lines and organoids.toolTODO::(add tool)urlhttps://cog.sanger.ac.uk/cmp/download/rnaseq_all_20220624.zipannotationcnvdatatypegenesclassSummarizedExperimentfilenameWES_pureCN_CNV_genes_20221213.csvdata_source   date2024-02-26 19:50:17numSamples934descriptionTotal copy number and categorical CNA calls derived from WES data processed through PureCN.toolTODO::(add tool)urlhttps://cog.sanger.ac.uk/cmp/download/WES_pureCN_CNV_genes_20221213.zipannotationcnvdatatypegenes_cn_categoryclassSummarizedExperimentfilenameWES_pureCN_CNV_genes_cn_category_20221213.csvdata_source   date2024-02-26 19:50:17numSamples934descriptionTotal copy number and categorical CNA calls derived from WES data processed through PureCN.toolTODO::(add tool)urlhttps://cog.sanger.ac.uk/cmp/download/WES_pureCN_CNV_genes_20221213.zipannotationfusiondatatype classSummarizedExperimentfilenameFusions_20230725.zipdata_source   date2024-02-26 19:50:17numSamples934descriptionTODO::(add description)toolTODO::(add tool)urlhttps://cog.sanger.ac.uk/cmp/download/Fusions_20230725.zip   filenameGDSC2_public_raw_data.csv; GDSC2_fitted_dose_response.xlsxdata_source   date2024-02-26descriptionThe raw data for the GDSC2 release 8.5 is available from the GDSC website.toolTODO::(add tool)urlhttps://www.cancerrxgene.org/downloads/bulk_downloadnumSamples1000sampleAnnotations   GDSC.sampleidGDSC.Sample_NameCMP.model_idcellosaurus.acccellosaurus.idcellosaurus.samplingSitecellosaurus.diseasesetc...numTreatments539treatmentAnnotations   pubchem.ChEMBL.IDGDSC.treatmentidGDSC.DRUG_IDpubchem.CIDpubchem.InChIKeypubchem.NSC.Numberpubchem.DILI.Statuspubchem.CAS.Numberpubchem.ATC.Codeetc...

Python Pydantic class definitions of the json

import datetime from typing import List, Optional from pydantic import BaseModel, Field class DataSource_DNL(BaseModel): description: str tool: Optional[str] = None url: str class MolecularProfile_DNL(BaseModel): annotation: str datatype: str class_: str = Field(alias="class") filename: str data_source: DataSource_DNL date: datetime.datetime numSamples: int class TreatmentResponse_DNL(BaseModel): filename: str data_source: DataSource_DNL date: datetime.datetime class SampleMetadata_DNL(BaseModel): numSamples: int sampleAnnotations: List[str] class TreatmentMetadata_DNL(BaseModel): numTreatments: int treatmentAnnotations: List[str] class PharmacoSet_DNL(BaseModel): MolecularProfiles: List[MolecularProfile] treatmentResponse: List[TreatmentResponse] sampleMetadata: SampleMetadata treatmentMetadata: TreatmentMetadata
Last modified: 28 May 2024