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A data.frame containing cell line Sentrix array metadata for the Genomics of Drug Sensitivity in Cancer (GDSC) dataset.

Source: R/CBWWorkshop2024_module1_data.R
GDSC_methylation_model_list.Rd

This is an annotation file of the GDSC methylation dataset from Iorio et al. 2016 containing Sentrix array platform metadata for cell lines with methylation profiling.

Usage

data(GDSC_methylation_model_list)

Format

data.frame object

References

  1. Yang, W., Soares, J., Greninger, P., Edelman, E. J., Lightfoot, H., Forbes, S., Bindal, N., Beare, D., Smith, J. A., Thompson, I. R., Ramaswamy, S., & Futreal, P. A. (2013). Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells. Nucleic Acids Research, 41(D1), D955–D961. https://doi.org/10.1093/nar/gks1111

  2. Iorio, F., Knijnenburg, T. A., Vis, D. J., Bignell, G. R., Menden, M. P., Schubert, M., Aben, N., Gonçalves, E., Barthorpe, S., Lightfoot, H., Cokelaer, T., Greninger, P., van Dyk, E., Chang, H., de Silva, H., Heyn, H., Deng, X., Egan, R. K., Liu, Q., Mironenko, T., … Garnett, M. J. (2016). A Landscape of Pharmacogenomic Interactions in Cancer. Cell, 166(3), 740–754. https://doi.org/10.1016/j.cell.2016.06.017

  3. Garnett, M. J., Edelman, E. J., Heidorn, S. J., Greenman, C. D., Dastur, A., Lau, K. W., Greninger, P., Thompson, I. R., Luo, X., Soares, J., Liu, Q., Iorio, F., Surdez, D., Chen, L., Milano, R. J., Bignell, G. R., Tam, A. T., Davies, H., Stevenson, J. A., … Benes, C. H. (2012). Systematic identification of genomic markers of drug sensitivity in cancer cells. Nature, 483(7391), 570–575. https://doi.org/10.1038/nature11005