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A data.frame containing metadata for cell lines used in the Genomics of Drug Sensitivity in Cancer (GDSC) project.

Source: R/CBWWorkshop2024_module1_data.R
GDSC_model_list.Rd

This is an annotation file of the GDSC dataset from Iorio et al. 2016 containing a list of cell line models used, including metadata for each cell line.

Usage

data(GDSC_model_list)

Format

data.frame object

References

  1. Yang, W., Soares, J., Greninger, P., Edelman, E. J., Lightfoot, H., Forbes, S., Bindal, N., Beare, D., Smith, J. A., Thompson, I. R., Ramaswamy, S., & Futreal, P. A. (2013). Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells. Nucleic Acids Research, 41(D1), D955–D961. https://doi.org/10.1093/nar/gks1111

  2. Iorio, F., Knijnenburg, T. A., Vis, D. J., Bignell, G. R., Menden, M. P., Schubert, M., Aben, N., Gonçalves, E., Barthorpe, S., Lightfoot, H., Cokelaer, T., Greninger, P., van Dyk, E., Chang, H., de Silva, H., Heyn, H., Deng, X., Egan, R. K., Liu, Q., Mironenko, T., … Garnett, M. J. (2016). A Landscape of Pharmacogenomic Interactions in Cancer. Cell, 166(3), 740–754. https://doi.org/10.1016/j.cell.2016.06.017

  3. Garnett, M. J., Edelman, E. J., Heidorn, S. J., Greenman, C. D., Dastur, A., Lau, K. W., Greninger, P., Thompson, I. R., Luo, X., Soares, J., Liu, Q., Iorio, F., Surdez, D., Chen, L., Milano, R. J., Bignell, G. R., Tam, A. T., Davies, H., Stevenson, J. A., … Benes, C. H. (2012). Systematic identification of genomic markers of drug sensitivity in cancer cells. Nature, 483(7391), 570–575. https://doi.org/10.1038/nature11005