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A TreatmentResponseExperiment containing RNA microarray, mircoRNA and RNA sequencing data from the NCI60, subset to cell-lines in NCI-ALMANAC

Source: R/CBWWorkshop2024_NCI-Almanac_data.R
NCI_ALMANAC_TRE.Rd

This data has been precurated for inclusion in the NCI60_2021 PharmacoSet, hosted on www.ORCESTRA.ca and downloadable from PharmacoGx via the downloadPSet function. This data has already been subset to contain only cancer cell-lines also present in the NCI-ALMANAC dataset.

Usage

data(NCI_ALMANAC_TRE)

CBWWorkshop2024::NCI_ALMANAC_TRE

NCI_ALMANAC_TRE

Format

TreatmentResponseExperiment object

An object of class TreatmentResponseExperiment with 6561 rows and 62 columns.

References

  1. Shoemaker, R. H. (2006). The NCI60 human tumour cell line anticancer drug screen. Nature Reviews Cancer, 6(10), 813–823. https://doi.org/10.1038/nrc1951

  2. Holbeck, S. L., Camalier, R., Crowell, J. A., Govindharajulu, J. P., Hollingshead, M., Anderson, L. W., Polley, E., Rubinstein, L., Srivastava, A., Wilsker, D., Collins, J. M., & Doroshow, J. H. (2017). The National Cancer Institute ALMANAC: A Comprehensive Screening Resource for the Detection of Anticancer Drug Pairs with Enhanced Therapeutic Activity. Cancer Research, 77(13), 3564–3576. https://doi.org/10.1158/0008-5472.CAN-17-0489